LoadCase package

This module contains functions that define interaction between various parts of the mitotic spindle, create compressive loads and specify boundary conditions as well as formulate the buckling step analysis.

Submodules

LoadCase.Interaction module

LoadCase.Interaction.CoupleAMTs(**kwargs)

Couple astral microtubules with springs

Parameters:kwargs – object Returns:None

LoadCase.Interaction.CoupleAMTsToCentrosomes(**kwargs)

Connect astral microtubules to centrosomes

Parameters:kwargs – object Returns:None

LoadCase.Interaction.CoupleIpMTsToCentrosomes(**kwargs)

Connect and couple interpolar microtubules to centrosomes

Parameters:kwargs – object Returns:None

LoadCase.Interaction.CoupleIpMTsToSring(data, **kwargs)

Create distributed elastic spring and couple interpolar microtubules to it

Parameters:kwargs – object Returns:None

LoadCase.Interaction.create_interactions(**kwargs)

Define all interactions and connections within model

Parameters:kwargs – object Returns:kwargs Return type:object Returns:data Return type:list

LoadCase.InteractionHelpers module

LoadCase.InteractionHelpers.attach_spring(region, dof, name, springType='Ground', **kwargs)

Defines a spring object that couples two points or a point to the ground

Parameters:

• region (str) – Name of the region to which spring is attached
• dof (int) – Number of DOF associated with the spring.
• name (str) – name of the spring connection
• springType (str) – Type of the spring. Either Ground or Pair
• kwargs (dict) – model parameters

Returns:

Null

Return type:

Null

LoadCase.InteractionHelpers.couple_nearest_aMTs(i, **kwargs)

Create a spring-based coupling of pairs of astral microtubules

Parameters:

• i (int) – Number of aMT
• kwargs (dict) – model parameters

Returns:

Null

Return type:

Null

LoadCase.InteractionHelpers.coupling_constraint(region1, region2, influenceRadius, couplingType, weightingMethod, name, **kwargs)

Create a coupling constraint between two regions

Parameters:

• region1 (object) – Master region
• region2 (object) – Slave region
• influenceRadius (float) – The influence of the master region will be distributed throughout the subregion in the slave region defined by this radius
• couplingType – Type of coupling is DISTRIBUTED ot STRUCTURAL
• weightingMethod (str) – Method of averaging the parameters of the coupling
• name (str) – Name of the coupling region
• kwargs (dict) – model parameters

Returns:

Null

Return type:

Null

LoadCase.InteractionHelpers.create_RP(**kwargs)

Create a reference point

Parameters:kwargs – object Returns:reference point object

LoadCase.InteractionHelpers.find_nearest(position, regions)

Find the astral microtubules that have the closest positions

Parameters:

• position (tuple) – (x, y, z) position of the aMT growing end
• regions (list of objects) – Regions that contain nearest aMT ends

Returns:

Null

Return type:

Null

LoadCase.InteractionHelpers.pick_region(verts_index, regionType, collectionName, position, **kwargs)

Pick a region to assign connection

Parameters:

• regionType – ‘vertice’, ‘edge’, ‘centrosome’ -> defines the type of the picked region
• collectionName – name of the entity specified by the region
• position – ‘centrosome-right’, ‘centrosome-left’ -> defines to which pole the region belongs
• kwargs – object

Returns:

(object) region

LoadCase.InteractionHelpers.sum_regions(verts_index, regionType, collectionName, separate='True', **kwargs)

Split a single picked region into a collection of sub-regions

Parameters:

• regionType – ‘vertice’, ‘edge’, ‘centrosome’ -> defines the type of the picked region
• collectionName – name of the entity specified by the region
• separate – ‘True’ -> separate combined region into right and left sub-regions
• kwargs – opbject

Returns:

either combined_region or combined_region_right and combined_region_left

LoadCase.LoadsAndBCs module

LoadCase.LoadsAndBCs.create_bc(**kwargs)

Fix growing ends of aMTs where they are attached to the membrane

Parameters:kwargs (dict) – model parameters Returns:Null Return type:Null

LoadCase.LoadsAndBCs.create_load(data, **kwargs)

Create and apply compressing load at each connection between connectors and ipMTs

Parameters:

• data (list) – list containing all ipMTs and connectors of the model
• kwargs (dict) – model parameters

Returns:

Null

Return type:

Null

LoadCase.Step module

LoadCase.Step.Step(**kwargs)

Create buckling analysis and define all the parameters

Parameters:kwargs (dict) – model parameters Returns:Null Return type:Null

Module contents